If no medical benefits are claimed, colloidal silver is sold as a supplement, and as long as the products comply with all other FDA regulations, its sale is considered legal. The FDA has issued warnings to Internet sites selling or promoting colloidal silver as an antibiotic or for other medical purposes. Such testing has not been conducted with colloidal silver, so the product now has the status of a dietary supplement in the US (dietary supplements cannot claim to cure diseases, only that they "support healthy functioning"). Unless a drug has undergone the rigorous safety and efficacy testing required of pharmaceuticals no medical benefits can be claimed. Food and Drug Administration (FDA) issued a ruling banning colloidal silver sellers from claiming any therapeutic value for the product. Many scientific articles report cases of argyria after ingestion of colloidal silver. Death of a 71 year old man has been reported following four months use of oral colloidal silver. While generally considered permanent, some have claimed to have reversed it. It can occur both via ingestion of silver, or through topical application of silver to the skin. It occurs when sunlight interacts with silver deposited in the skin, in the same way that silver particles in photographic film darken when exposed to sunlight. Long-term intake of silver products may result in a condition known as argyria, one symptom of which is a blue or gray discoloration of the skin. Method of ActionĬolloidal silver is reported to kill bacteria via the oligodynamic effect by inhibiting the expression of enzymes and other proteins essential to ATP production. (Silver nitrate solutions are not the same thing as a suspension of colloidal silver.) Silver-containing cremes such as silver sulfadiazine have been used in burn centers for more than 100 years. Silver nitrate solutions were introduced by Credé in 1880 to protect newborn infants' eyes from infection, but have largely been replaced by antibiotic ointments since 1978. ![]() ![]() Ĭompounds of silver also have a long history in medicine. Colloidal silver has been approved by the EPA as a disinfectant for hospitals and medical centers. But the material was costly and the pharmaceutical industry developed fast-acting, less-expensive sulfa drugs and penicillin. It was produced by pharmaceutical companies under various names, including Protargol and Argyrol. Prior to 1938, colloidal silver was widely used by physicians as a mainstream antibiotic. ![]() Colloidal silver with concentrations of 30 parts per million (ppm) or less are typically manufactured using an electrolysis process, whereas colloidal silver with higher concentrations of 50 ppm or more are usually either silver compounds such as silver chloride and silver iodide or are solutions that have been bound with a protein to disperse the particles.Ĭoncentrations of colloidal silver at 5 parts per million or higher have been found to kill numerous infectious bacteria. The broader commercial definition of "colloidal silver" includes products that contain various concentrations of ionic silver, silver colloids, ionic silver compounds or silver proteins in purified water. A colloid is technically defined as particles which remain suspended without forming an ionic, or dissolved solution. List of terms related to Colloidal silverĬolloidal silver is a liquid suspension of microscopic particles of silver. Risk calculators and risk factors for Colloidal silverĬauses & Risk Factors for Colloidal silver US National Guidelines Clearinghouse on Colloidal silverĭirections to Hospitals Treating Colloidal silver Ongoing Trials on Colloidal silver at Clinical Ĭlinical Trials on Colloidal silver at Google ![]() Articles on Colloidal silver in N Eng J Med, Lancet, BMJĬochrane Collaboration on Colloidal silver
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